Pesquisa | Secretaria de Estado da Saúde

1.

Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults.

Ravichandran, Sathyabaarathi; Erra-Diaz, Fernando; Karakaslar, Onur E; Marches, Radu; Kenyon-Pesce, Lisa; Rossi, Robert; Chaussabel, Damien; Nehar-Belaid, Djamel; LaFon, David C; Pascual, Virginia; Palucka, Karolina; Paust, Silke; Nahm, Moon H; Kuchel, George A; Banchereau, Jacques; Ucar, Duygu.

Nat Immunol ; 25(2): 316-329, 2024 Feb.

Artigo Inglês | MEDLINE | ID: mdl-38182669

2.

Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly.

Giamarellos-Bourboulis, Evangelos J; Tsilika, Maria; Moorlag, Simone; Antonakos, Nikolaos; Kotsaki, Antigone; Domínguez-Andrés, Jorge; Kyriazopoulou, Evdoxia; Gkavogianni, Theologia; Adami, Maria-Evangelia; Damoraki, Georgia; Koufargyris, Panagiotis; Karageorgos, Athanassios; Bolanou, Amalia; Koenen, Hans; van Crevel, Reinout; Droggiti, Dionyssia-Irene; Renieris, George; Papadopoulos, Antonios; Netea, Mihai G.

Cell ; 183(2): 315-323.e9, 2020 10 15.

Artigo Inglês | MEDLINE | ID: mdl-32941801

3.

Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.

Jochems, Simon P; Marcon, Fernando; Carniel, Beatriz F; Holloway, Mark; Mitsi, Elena; Smith, Emma; Gritzfeld, Jenna F; Solórzano, Carla; Reiné, Jesús; Pojar, Sherin; Nikolaou, Elissavet; German, Esther L; Hyder-Wright, Angie; Hill, Helen; Hales, Caz; de Steenhuijsen Piters, Wouter A A; Bogaert, Debby; Adler, Hugh; Zaidi, Seher; Connor, Victoria; Gordon, Stephen B; Rylance, Jamie; Nakaya, Helder I; Ferreira, Daniela M.

Nat Immunol ; 19(12): 1299-1308, 2018 12.

Artigo Inglês | MEDLINE | ID: mdl-30374129

4.

Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response.

Golebski, Korneliusz; Layhadi, Janice A; Sahiner, Umit; Steveling-Klein, Esther H; Lenormand, Madison M; Li, Rachael C Y; Bal, Suzanne M; Heesters, Balthasar A; Vilà-Nadal, Gemma; Hunewald, Oliver; Montamat, Guillem; He, Feng Q; Ollert, Markus; Fedina, Oleksandra; Lao-Araya, Mongkol; Vijverberg, Susanne J H; Maitland-van der Zee, Anke-Hilse; van Drunen, Cornelis M; Fokkens, Wytske J; Durham, Stephen R; Spits, Hergen; Shamji, Mohamed H.

Immunity ; 54(2): 291-307.e7, 2021 02 09.

Artigo Inglês | MEDLINE | ID: mdl-33450188

5.

A synergistic mindsets intervention protects adolescents from stress.

Yeager, David S; Bryan, Christopher J; Gross, James J; Murray, Jared S; Krettek Cobb, Danielle; H F Santos, Pedro; Gravelding, Hannah; Johnson, Meghann; Jamieson, Jeremy P.

Nature ; 607(7919): 512-520, 2022 07.

Artigo Inglês | MEDLINE | ID: mdl-35794485

6.

Combination anti-HIV antibodies provide sustained virological suppression.

Sneller, Michael C; Blazkova, Jana; Justement, J Shawn; Shi, Victoria; Kennedy, Brooke D; Gittens, Kathleen; Tolstenko, Jekaterina; McCormack, Genevieve; Whitehead, Emily J; Schneck, Rachel F; Proschan, Michael A; Benko, Erika; Kovacs, Colin; Oguz, Cihan; Seaman, Michael S; Caskey, Marina; Nussenzweig, Michel C; Fauci, Anthony S; Moir, Susan; Chun, Tae-Wook.

Nature ; 606(7913): 375-381, 2022 06.

Artigo Inglês | MEDLINE | ID: mdl-35650437

7.

Live, Attenuated, Tetravalent Butantan-Dengue Vaccine in Children and Adults.

Kallás, Esper G; Cintra, Monica A T; Moreira, José A; Patiño, Elizabeth G; Braga, Patricia Emilia; Tenório, Juliana C V; Infante, Vanessa; Palacios, Ricardo; de Lacerda, Marcus Vínicius Guimarães; Batista Pereira, Dhelio; da Fonseca, Allex Jardim; Gurgel, Ricardo Queiroz; Coelho, Ivo Castelo-Branco; Fontes, Cor Jesus Fernandes; Marques, Ernesto T A; Romero, Gustavo Adolfo Sierra; Teixeira, Mauro Martins; Siqueira, André M; Barral, Aldina Maria Prado; Boaventura, Viviane Sampaio; Ramos, Fabiano; Elias Júnior, Erivaldo; Cassio de Moraes, José; Covas, Dimas T; Kalil, Jorge; Precioso, Alexander Roberto; Whitehead, Stephen S; Esteves-Jaramillo, Alejandra; Shekar, Tulin; Lee, Jung-Jin; Macey, Julieta; Kelner, Sabrina Gozlan; Coller, Beth-Ann G; Boulos, Fernanda Castro; Nogueira, Mauricio L.

N Engl J Med ; 390(5): 397-408, 2024 Feb 01.

Artigo Inglês | MEDLINE | ID: mdl-38294972

8.

A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy.

Mathur, Mohit; Barratt, Jonathan; Chacko, Bobby; Chan, Tak Mao; Kooienga, Laura; Oh, Kook-Hwan; Sahay, Manisha; Suzuki, Yusuke; Wong, Muh Geot; Yarbrough, Jill; Xia, Jing; Pereira, Brian J G.

N Engl J Med ; 390(1): 20-31, 2024 Jan 04.

Artigo Inglês | MEDLINE | ID: mdl-37916620

9.

Trial of Lixisenatide in Early Parkinson's Disease.

Meissner, Wassilios G; Remy, Philippe; Giordana, Caroline; Maltête, David; Derkinderen, Pascal; Houéto, Jean-Luc; Anheim, Mathieu; Benatru, Isabelle; Boraud, Thomas; Brefel-Courbon, Christine; Carrière, Nicolas; Catala, Hélène; Colin, Olivier; Corvol, Jean-Christophe; Damier, Philippe; Dellapina, Estelle; Devos, David; Drapier, Sophie; Fabbri, Margherita; Ferrier, Vanessa; Foubert-Samier, Alexandra; Frismand-Kryloff, Solène; Georget, Aurore; Germain, Christine; Grimaldi, Stéphane; Hardy, Clémence; Hopes, Lucie; Krystkowiak, Pierre; Laurens, Brice; Lefaucheur, Romain; Mariani, Louise-Laure; Marques, Ana; Marse, Claire; Ory-Magne, Fabienne; Rigalleau, Vincent; Salhi, Hayet; Saubion, Amandine; Stott, Simon R W; Thalamas, Claire; Thiriez, Claire; Tir, Mélissa; Wyse, Richard K; Benard, Antoine; Rascol, Olivier.

N Engl J Med ; 390(13): 1176-1185, 2024 Apr 04.

Artigo Inglês | MEDLINE | ID: mdl-38598572

10.

An Oral Interleukin-23-Receptor Antagonist Peptide for Plaque Psoriasis.

Bissonnette, Robert; Pinter, Andreas; Ferris, Laura K; Gerdes, Sascha; Rich, Phoebe; Vender, Ronald; Miller, Megan; Shen, Yaung-Kaung; Kannan, Arun; Li, Shu; DeKlotz, Cynthia; Papp, Kim.

N Engl J Med ; 390(6): 510-521, 2024 Feb 08.

Artigo Inglês | MEDLINE | ID: mdl-38324484

11.

Rusfertide, a Hepcidin Mimetic, for Control of Erythrocytosis in Polycythemia Vera.

Kremyanskaya, Marina; Kuykendall, Andrew T; Pemmaraju, Naveen; Ritchie, Ellen K; Gotlib, Jason; Gerds, Aaron; Palmer, Jeanne; Pettit, Kristen; Nath, Uttam K; Yacoub, Abdulraheem; Molina, Arturo; Saks, Samuel R; Modi, Nishit B; Valone, Frank H; Khanna, Sarita; Gupta, Suneel; Verstovsek, Srdan; Ginzburg, Yelena Z; Hoffman, Ronald.

N Engl J Med ; 390(8): 723-735, 2024 Feb 22.

Artigo Inglês | MEDLINE | ID: mdl-38381675

12.

A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.

Harrison, Stephen A; Bedossa, Pierre; Guy, Cynthia D; Schattenberg, Jörn M; Loomba, Rohit; Taub, Rebecca; Labriola, Dominic; Moussa, Sam E; Neff, Guy W; Rinella, Mary E; Anstee, Quentin M; Abdelmalek, Manal F; Younossi, Zobair; Baum, Seth J; Francque, Sven; Charlton, Michael R; Newsome, Philip N; Lanthier, Nicolas; Schiefke, Ingolf; Mangia, Alessandra; Pericàs, Juan M; Patil, Rashmee; Sanyal, Arun J; Noureddin, Mazen; Bansal, Meena B; Alkhouri, Naim; Castera, Laurent; Rudraraju, Madhavi; Ratziu, Vlad.

N Engl J Med ; 390(6): 497-509, 2024 02 08.

Artigo Inglês | MEDLINE | ID: mdl-38324483

13.

Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes.

Kosiborod, Mikhail N; Petrie, Mark C; Borlaug, Barry A; Butler, Javed; Davies, Melanie J; Hovingh, G Kees; Kitzman, Dalane W; Møller, Daniél V; Treppendahl, Marianne B; Verma, Subodh; Jensen, Thomas J; Liisberg, Karoline; Lindegaard, Marie L; Abhayaratna, Walter; Ahmed, Fozia Z; Ben-Gal, Tuvia; Chopra, Vijay; Ezekowitz, Justin A; Fu, Michael; Ito, Hiroshi; Lelonek, Malgorzata; Melenovský, Vojtech; Merkely, Bela; Núñez, Julio; Perna, Eduardo; Schou, Morten; Senni, Michele; Sharma, Kavita; van der Meer, Peter; Von Lewinski, Dirk; Wolf, Dennis; Shah, Sanjiv J.

N Engl J Med ; 390(15): 1394-1407, 2024 04 18.

Artigo Inglês | MEDLINE | ID: mdl-38587233

14.

Trial of N-Acetyl-l-Leucine in Niemann-Pick Disease Type C.

Bremova-Ertl, Tatiana; Ramaswami, Uma; Brands, Marion; Foltan, Tomas; Gautschi, Matthias; Gissen, Paul; Gowing, Francesca; Hahn, Andreas; Jones, Simon; Kay, Richard; Kolnikova, Miriam; Arash-Kaps, Laila; Marquardt, Thorsten; Mengel, Eugen; Park, Julien H; Reichmannová, Stella; Schneider, Susanne A; Sivananthan, Siyamini; Walterfang, Mark; Wibawa, Pierre; Strupp, Michael; Martakis, Kyriakos.

N Engl J Med ; 390(5): 421-431, 2024 Feb 01.

Artigo Inglês | MEDLINE | ID: mdl-38294974

15.

Empagliflozin after Acute Myocardial Infarction.

Butler, Javed; Jones, W Schuyler; Udell, Jacob A; Anker, Stefan D; Petrie, Mark C; Harrington, Josephine; Mattheus, Michaela; Zwiener, Isabella; Amir, Offer; Bahit, M Cecilia; Bauersachs, Johann; Bayes-Genis, Antoni; Chen, Yundai; Chopra, Vijay K; Figtree, Gemma; Ge, Junbo; Goodman, Shaun G; Gotcheva, Nina; Goto, Shinya; Gasior, Tomasz; Jamal, Waheed; Januzzi, James L; Jeong, Myung Ho; Lopatin, Yuri; Lopes, Renato D; Merkely, Béla; Parikh, Puja B; Parkhomenko, Alexander; Ponikowski, Piotr; Rossello, Xavier; Schou, Morten; Simic, Dragan; Steg, P Gabriel; Szachniewicz, Joanna; van der Meer, Peter; Vinereanu, Dragos; Zieroth, Shelley; Brueckmann, Martina; Sumin, Mikhail; Bhatt, Deepak L; Hernandez, Adrian F.

N Engl J Med ; 390(16): 1455-1466, 2024 Apr 25.

Artigo Inglês | MEDLINE | ID: mdl-38587237

16.

Testosterone Treatment and Fractures in Men with Hypogonadism.

Snyder, Peter J; Bauer, Douglas C; Ellenberg, Susan S; Cauley, Jane A; Buhr, Kevin A; Bhasin, Shalender; Miller, Michael G; Khan, Nader S; Li, Xue; Nissen, Steven E.

N Engl J Med ; 390(3): 203-211, 2024 Jan 18.

Artigo Inglês | MEDLINE | ID: mdl-38231621

17.

Inhibition of CD40L with Frexalimab in Multiple Sclerosis.

Vermersch, Patrick; Granziera, Cristina; Mao-Draayer, Yang; Cutter, Gary; Kalbus, Oleksandr; Staikov, Ivan; Dufek, Michal; Saubadu, Stephane; Bejuit, Raphael; Truffinet, Philippe; Djukic, Biljana; Wallstroem, Erik; Giovannoni, Gavin.

N Engl J Med ; 390(7): 589-600, 2024 Feb 15.

Artigo Inglês | MEDLINE | ID: mdl-38354138

18.

Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.

Healey, Jeff S; Lopes, Renato D; Granger, Christopher B; Alings, Marco; Rivard, Lena; McIntyre, William F; Atar, Dan; Birnie, David H; Boriani, Giuseppe; Camm, A John; Conen, David; Erath, Julia W; Gold, Michael R; Hohnloser, Stefan H; Ip, John; Kautzner, Josef; Kutyifa, Valentina; Linde, Cecilia; Mabo, Philippe; Mairesse, Georges; Benezet Mazuecos, Juan; Cosedis Nielsen, Jens; Philippon, Francois; Proietti, Marco; Sticherling, Christian; Wong, Jorge A; Wright, David J; Zarraga, Ignatius G; Coutts, Shelagh B; Kaplan, Andrew; Pombo, Marta; Ayala-Paredes, Felix; Xu, Lizhen; Simek, Kim; Nevills, Sandra; Mian, Rajibul; Connolly, Stuart J.

N Engl J Med ; 390(2): 107-117, 2024 Jan 11.

Artigo Inglês | MEDLINE | ID: mdl-37952132

19.

Benralizumab versus Mepolizumab for Eosinophilic Granulomatosis with Polyangiitis.

Wechsler, Michael E; Nair, Parameswaran; Terrier, Benjamin; Walz, Bastian; Bourdin, Arnaud; Jayne, David R W; Jackson, David J; Roufosse, Florence; Börjesson Sjö, Lena; Fan, Ying; Jison, Maria; McCrae, Christopher; Necander, Sofia; Shavit, Anat; Walton, Claire; Merkel, Peter A.

N Engl J Med ; 390(10): 911-921, 2024 Mar 07.

Artigo Inglês | MEDLINE | ID: mdl-38393328

20.

Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma.

Choueiri, Toni K; Tomczak, Piotr; Park, Se Hoon; Venugopal, Balaji; Ferguson, Tom; Symeonides, Stefan N; Hajek, Jaroslav; Chang, Yen-Hwa; Lee, Jae-Lyun; Sarwar, Naveed; Haas, Naomi B; Gurney, Howard; Sawrycki, Piotr; Mahave, Mauricio; Gross-Goupil, Marine; Zhang, Tian; Burke, John M; Doshi, Gurjyot; Melichar, Bohuslav; Kopyltsov, Evgeniy; Alva, Ajjai; Oudard, Stephane; Topart, Delphine; Hammers, Hans; Kitamura, Hiroshi; McDermott, David F; Silva, Adriano; Winquist, Eric; Cornell, Jerry; Elfiky, Aymen; Burgents, Joseph E; Perini, Rodolfo F; Powles, Thomas.

N Engl J Med ; 390(15): 1359-1371, 2024 Apr 18.

Artigo Inglês | MEDLINE | ID: mdl-38631003

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